Molecular Microbiology
and Enzymology

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Christoph Mayer, Heisenberg Research Group of the DFG

Bacterial Cell Wall Metabolism & Enzymology of Carbohydrate Active Enzymes

Research in my group is located in the intercept between chemistry and biology.
Our major goal is to understand biological systems at the molecular level
and our affort currently focuses on following topics:

  1. Identification of novel enzymes and elucidation of structure, function, and mechanism of enzymes involved in the bacterial cell wall recycling pathway
  2. Elucidation of aminosugar metabolic pathways and their regulation in environmental and pathogenic microorganisms
  3. Protein engineering (directed evolution) of protein function and metabolic engineering (cell wall engineering)

Some of our current projects are:

  • Cell wall recycling metabolism in E. coli and B. subtilis
  • Adaptation of peptidoglycan catabolism in pathogenic and environmental bacteria
  • Structure and mechanism of MurNAc etherases (carbon-oxygen lyases/hydrolases)
  • Structure and mechanism of (anhydro)MurNAc kinases
  • Structure and mechanism of regulators of MurNAc metabolism

More Information regarding our research can be found here:

BioSpektrum 5/2005 or 5/2010

BioLago deutsch or english

!!! Jonathan Gisin erhält

ein "Dr. Marietta-Lutze-Stipendium" der Firma Dr. Kade AG