Molecular Microbiology
and Enzymology

Login |
 
 

Selected Publications:

  1. Litzinger, S., Fischer, S., Polzer, P., Diederichs, K., Welte, W., Mayer, C. (2010)
    Structural and kinetic analysis of Bacillus subtilis N-acetylglucosaminidase reveals a unique Asp-His dyad mechanism. J. Biol. Chem. in press, doi: 10.1074/ jbc.M110.131037
  2. Litzinger S, Duckworth A, Nitzsche K, Risinger C, Wittmann V, Mayer C. (2010)
    Muropeptide rescue in Bacillus subtilis involves sequential hydrolysis by beta-N-acetylglucosaminidase and N-acetylmuramyl-L-alanine amidase.
    J Bacteriol. 192(12):3132-43.
  3. Litzinger, S. Mayer, C. (2010) Chapter 1: The murein sacculus
    In H. König, H. Claus, A. Varma (eds.), Prokaryotic cell wall compounds – structure and biochemistry, Springer, Berlin, Heidelberg, 3-54.
  4. Hadi, T., Dahl, U., Mayer, C., Tanner, M. (2008)
    Mechanistic studies on N-acetylmuramic acid 6-phosphate hydrolase (MurQ): an etherase involved in peptidoglycan recycling.
    Biochemistry 47(44):11547-58.
  5. Jaeger, T., Mayer, C. (2008)
    The transcriptional factors MurR and catabolite activator protein regulate the N-acetylmuramic acid metabolism in Escherichia coli.
    J. Bacteriol. 190, 6598-6608.
  6. Jaeger, T., Mayer, C. (2008)
    The N-acetylmuramic acid 6-phosphate lyases (MurNAc etherases).
    Cell. Mol. Life Sci. 65, 928-939.
  7. Draing C, Sigel S, Deininger S, Traub S, Munke R, Mayer C, Hareng L, Hartung T, von Aulock S, Hermann C.
    Cytokine induction by Gram-positive bacteria.
    Immunobiology. 2008;213(3-4):285-96. Epub 2008 Feb 19.
  8. Qu, J., Mayer, C., Behrens, S., Holst, O., Kleinschmidt, J. (2007)
    The trimeric periplasmic chaperon Skp of E. coli froms 1:1 complexes with outer membrane proteins via hydrophobic and electrostatic interactions. J. Mol.Biol. 374, 91-105.
  9. Mayer, C., Vocadlo, D.J., Mah, M., Rupitz, K., Stoll, D., Warren, R.A.J., Withers, S.G. (2006)
    Characterization of a beta-N-acetylglucosaminidase/beta-glucosidase from Cellulomonas fimi.
    FEBS J. 273, 2929-2941.
  10. Uehara, T., Suefuji, K., Jaeger, T., Mayer, C. & Park, J.T. (2006)
    MurQ etherase is required by Escherichia coli in order to metabolize anydro-N-Acetylmuramic acid obtained either from the environment or from its own cell wall.
    J. Bacteriol., 188, 1660-1662.
  11. Mayer, C. (2005)
    Wie Bakterien ihre Verpackung wiederverwerten: Mureinabbau und Recycling.
    BIOspektrum 5, 616-619.
  12. Jaeger, T. Arsic, M, & Mayer, C. (2005)
    Scission of the lactyl ether bond of N-acetyl muramic acid by Escherichia coli "etherase".
    J. Biol. Chem., 280, 30100-30106.
  13. Mayer, C. & Boos W. (2005)
    march 29th posting date, Chapter 3.4.1 Hexose/pentose and hexitol/pentitol metabolism.
    In Bock, A., Curtiss, III. R., Kaper, J.B., Neidhardt, F.C., Nystrom, T., Rudd, K.E., and Squires, C.L. (ed.), EcoSal-Escherichia coli and Salmonella: Cellular and Molecular Biology.
    [Online.] www.ecosal.org ASM Press, Washington, D.C.
  14. Dahl, U., Jaeger, T., Nguyen, B.T., Sattler, J.M., & Mayer, C. (2004)
    Identification of a phosphotransferase system of Escherichia coli required for growth on N-acetylmuramic acid.
    J. Bacteriol. 186, 2385-2392.
  15. Rast, D. M., Baumgartner, D., Mayer, C., & Hollenstein, G. O. (2003)
    Cell wall-associated enzymes in fungi.
    Phytochemistry 64, 339-366.
  16. Tolborg, J. F., Petersen, L., Jensen, K. J., Mayer, C., Jakeman, D. L., Warren, R. A., & Withers, S. G. (2002)
    Solid-phase oligosaccharide and glycopeptide synthesis using glycosynthases.
    J. Org. Chem. 67, 4243-4249.
  17. Mayer, C., Jakeman, D., Mah, M., Gal, L. Karjala, G., Warren, R.A.J. & Withers, S.G. (2001)
    Directed evolution of new glycosynthases from Agrobacterium beta-glucosynthase: A general screen to detect enzymes for oligosaccharide synthesis.
    Chem. Biol. 8, 437-443.
  18. Zechel, D.L., Reid, S.P., Nashiru, O., Mayer, C., Stoll, D., Jakeman, D.,L., Warren, R.A., Withers, S.G. (2001)
    Enzymatic synthesis of carbon-fluorine bonds.
    J. Am. Chem. Soc. 123, 4350-4351.
  19. Mayer, C., Zechel, D., Warren, R.A.J. & Withers, S.G. (2000)
    E358S mutant of Agrobacterium sp. beta-glucosidase is a greatly improved glycosynthase.
    FEBS letters 466, 40-44.
  20. Mayer, C., Vocadlo, D., and Withers, S.G. (2000)
    beta-N-Acetylhexosaminidases: two enzyme families, two mechanisms.
    In M.G. Peter, Muzzarelli, R.A.A., Domard, A., eds., Advances in Chitin Science
    Vol. 4, pp. 612, European Chitin Society.
  21. Vocadlo, D. Mayer, C., He, S. and Withers, S.G. (2000)
    Mechanism of action and identification of Asp242 as the catalytic nucleophile of Vibrio furnisii
    N    -Acetyl-beta-D-glucosaminidase using 2-acetamido-2-deoxy-5-fluoro-alpha-L-idopyranosyl fluoride.
    Biochemistry 31, 117-126.