Research Training Group RTG 1331


Latest publications 2017


Bitzer A, Basler M, Krappmann D, Groettrup M (2017) Immunoproteasome subunit deficiency has no influence on the canonical pathway of NF-κB activation. Mol Immunol. 83:147-153. doi: 10.1016/j.molimm.2017.01.019. [Epub ahead of print]

Colaianna M, Ilmjärv S, Peterson H, Kern I, Julien S, Baquié M, Pallocca G, Bosgra S, Sachinidis A, Hengstler JG, Leist M, Krause KH. (2017) Fingerprinting of neurotoxic compounds using a mouse embryonic stem cell dual luminescence reporter assay. Arch Toxicol. 91(1):365-391

Efremova L, Chovancova P, Adam M, Gutbier S, Schildknecht S, Leist M. (2017) Switching from astrocytic neuroprotection to neurodegeneration by cytokine stimulation. Arch Toxicol. 91(1):231-246

Grabinger T, Bode KJ, Demgenski J, Seitz C, Delgado ME, Kostadinova F, Reinhold C, Etemadi N, Wilhelm S, Schweinlin M, Hänggi K, Knop J, Hauck C, Walles H, Silke J, Wajant H, Nachbur U, Wong WWL, Brunner T (2017) Inhibitor of Apoptosis Protein-1 Regulates Tumor Necrosis Factor-mediated Destruction of Intestinal Epithelial Cells. Gastroenterology, 152(4):867-879.

Hirsch C, Striegl B, Mathes S, Adlhart C, Edelmann M, Bono E, Gaan S, Salmeia KA, Hoelting L, Krebs A, Nyffeler J, Pape R, Bürkle A, Leist M, Wick P, Schildknecht S. (2017) Multiparameter toxicity assessment of novel DOPO-derived organophosphorus flame retardants. Arch Toxicol. 91(1):407-425.

Luks L, Maier MY, Sacchi S, Pollegioni L, Dietrich DR. (2017) Understanding renal nuclear protein accumulation: an in vitro approach to explain an in vivo phenomenon. Arch Toxicol. 2017 Apr 27. doi: 10.1007/s00204-017-1970-5. [Epub ahead of print]

Luks L, Sacchi S, Pollegioni L, Dietrich DR. (2017) Novel insights into renal D-amino acid oxidase accumulation: propiverine changes DAAO localization and peroxisomal size in vivo. Arch Toxicol. 91(1):427-437.

Nyffeler J, Dolde X, Krebs A, Pinto-Gil K, Pastor M, Behl M, Waldmann T, Leist M. (2017) Combination of multiple neural crest migration assays to identify environmental toxicants from a proof-of-concept chemical library. Arch Toxicol. 2017 May 5. doi: 10.1007/s00204-017-1977-y. [Epub ahead of print]

Nyffeler J, Karreman C, Leisner H, Kim YJ, Lee G, Waldmann T, Leist M. (2017) Design of a high-throughput human neural crest cell migration assay to indicate potential developmental toxicants ALTEX. 34(1):75-94

Pallocca G, Nyffeler J, Dolde X, Grinberg M, Gstraunthaler G, Waldmann T, Rahnenführer J, Sachinidis A, Leist M. (2017) Impairment of human neural crest cell migration by prolonged exposure to interferon beta. Arch Toxicol. 2017 Apr 1. doi: 10.1007/s00204-017-1966-1. [Epub ahead of print]

Sá JV, Kleiderman S, Brito C, Sonnewald U, Leist M, Teixeira AP, Alves PM (2017) Quantification of Metabolic Rearrangements During Neural Stem Cells Differentiation into Astrocytes by Metabolic Flux Analysis. Neurochem Res. 42(1):244-253

Schmidt BZ, Lehmann M, Gutbier S, Nembo E, Noel S, Smirnova L, Forsby A, Hescheler J, Avci HX, Hartung T, Leist M, Kobolák J, Dinnyés A.(2017) In vitro acute and developmental neurotoxicity screening: an overview of cellular platforms and high-throughput technical possibilities. Arch Toxicol. 91(1):1-33 Review.

Schwaderer J, Gaiser AK, Phan TS, Delgado ME, Brunner T. (2017) Liver receptor homolog-1 (NR5a2) regulates CD95/Fas ligand transcription and associated T-cell effector functions. Cell Death Dis. 2017 Apr 13;8(4):e2745. doi: 10.1038/cddis.2017.173

Spinnenhirn V, Bitzer A, Aichem A, Groettrup M. (2017) Newly translated proteins are substrates for ubiquitin, ISG15, and FAT10. FEBS Lett. 591(1):186-195.

Waldmann T, Grinberg M, König A, Rempel E, Schildknecht S, Henry M, Holzer AK, Dreser N, Shinde V, Sachinidis A, Rahnenführer J, Hengstler JG, Leist M. (2017) Stem Cell Transcriptome Responses and Corresponding Biomarkers That Indicate the Transition from Adaptive Responses to Cytotoxicity. Chem Res Toxicol. 2017 Apr 17;30(4):905-922. doi: 10.1021/acs.chemrestox.6b00259. Epub 2016 Dec 21.

Weidele K, Beneke S, Bürkle A. (2017) The NAD+ precursor nicotinic acid improves genomic integrity in human peripheral blood mononuclear cells after X-irradiation. DNA Repair (Amst). 2017 Apr;52:12-23. doi: 10.1016/j.dnarep.2017.02.001. Epub 2017 Feb 13.